Acute Respiratory Distress Syndrome Caused by Methadone Syrup

  • Abbas Aghabiklooei Firoozgar Teaching Hospital, Iran University of Medical Sciences
  • Shahin Shadnia Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences
  • Hossein Hassanian-Moghaddam Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences
  • Nasim Zamani Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences
Keywords: accidental intoxication, overdose, pulmonary oedema, respiratory complications

Abstract

Acute respiratory distress syndrome (ARDS) due to methadone (MTD) toxicity is a known but rather uncommon phenomenon. In most of the previously reported cases of MTD-related ARDS, MTD was ingested orally in the form of tablets in high or unknown amounts. Despite the findings from the available literature, this case report is aimed at demonstrating that even small amounts of MTD syrup can cause ARDS earlier than it is usually expected. We present a non-addicted MTD-overdosed patient who developed ARDS after ingesting a very small amount of MTD syrup. We suggest close monitoring of MTD-overdosed patients from at least 48 h to 72 h for possible respiratory complications such as pulmonary oedema. 

Published
2013-09-15
How to Cite
1.
Aghabiklooei A, Shadnia S, Hassanian-Moghaddam H, Zamani N. Acute Respiratory Distress Syndrome Caused by Methadone Syrup. Arh Hig Rada Toksikol [Internet]. 2013Sep.15 [cited 2024Apr.20];64(3). Available from: https://arhiv.imi.hr/index.php/arhiv/article/view/81
Section
Case report