Exposure to particulate matter: a brief review with a focus on cardiovascular effects, children, and research conducted in Turkey

  • Aylin Elkama Gazi University Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey
  • Ayça Aktaş Şüküroğlu Gazi University Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey
  • Gonca Çakmak Gazi University, Faculty of Pharmacy, Department of Toxicology
Keywords: air quality, cardiovascular toxicity, monitoring, regulations, vulnerable populations

Abstract

Exposure to environmental particulate matter (PM), outdoor air pollution in particular, has long been associated with adverse health effects. Today, PM has widely been accepted as a systemic toxicant showing adverse effects beyond the lungs. There are numerous studies, from those in vitro to epidemiological ones, suggesting various direct and indirect PM toxicity mechanisms associated with cardiovascular risks, including inflammatory responses, oxidative stress, changes in blood pressure, autonomic regulation of heart rate, suppression of endothelium-dependent vasodilation, thrombogenesis, myocardial infarction, and fibrinolysis. In addition to these and other health risks, considerations about air quality standards should include individual differences, lifestyle, and vulnerable populations such as children. Urban air pollution has been a major environmental issue for Turkey, and this review will also address current situation, research, and measures taken in our country.

Published
2021-12-08
How to Cite
1.
Elkama A, Şüküroğlu AA, Çakmak G. Exposure to particulate matter: a brief review with a focus on cardiovascular effects, children, and research conducted in Turkey. Arh Hig Rada Toksikol [Internet]. 2021Dec.8 [cited 2024May20];72(4). Available from: https://arhiv.imi.hr/index.php/arhiv/article/view/1419
Section
Review