Comparative analysis of organophosphorus versus carbamate pesticide poisoning: a case study

  • Jia-ding Xia Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
  • Hui Wang Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
  • Li-wei Hua Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
  • Min Xu Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
  • Xin Zheng Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
  • Kun Zhang Affiliated Hospital of Chengde Medical University, Department of Intensive Care, Chengde, China
Keywords: acetylcholinesterase, carbamate, carbofuran, cholinergic chrisis, dichlorvos, intensive care, organophosphates

Abstract

Organophosphorus poisoning is a critical condition that can cause central nervous system depression, respiratory failure, and death early on. As its clinical manifestations closely resemble those of carbamate pesticide poisoning, the aim of this case study is to present a case of misdiagnosis, initially identifying carbofuran poisoning as organophosphate in a patient suspect of a heatstroke. We also present a case of intentional self-poisoning with organophosphate dichlorvos to underline the likelihood of pesticide poisoning in patients exhibiting acute cholinergic symptoms when the ingested substance is not known. In such cases, empirical treatment with atropine and oxime can be started pending timely differential diagnosis to adjust treatment as necessary.

Published
2024-02-15
How to Cite
1.
Xia J- ding, Wang H, Hua L- wei, Xu M, Zheng X, Zhang K. Comparative analysis of organophosphorus versus carbamate pesticide poisoning: a case study. Arh Hig Rada Toksikol [Internet]. 2024Feb.15 [cited 2024Apr.19];75(1). Available from: https://arhiv.imi.hr/index.php/arhiv/article/view/1641
Section
Case study