Endocrine, Lifestyle, and Genetic Factors in the Development of Metabolic Syndrome

Authors

  • Zorana Slanovic Kuzmanović Faculty of Pharmacy and Biochemistry, University of Zagreb
  • Ivan Kos Faculty of Pharmacy and Biochemistry, University of Zagreb
  • Ana-Marija Domijan Faculty of Pharmacy and Biochemistry, University of Zagreb

DOI:

https://doi.org/10.2478/10004-1254-64-2013-2327

Keywords:

cardiovascular diseases, circadian rhythm, hyperglycaemia, hypertension cortisol, insulin, MetS, type 2 diabetes

Abstract

Metabolic syndrome (MetS) is a chronic, multi-component disease characterised by central obesity, hyperglycaemia, dyslipidaemia, and hypertension. Since MetS leads to type 2 diabetes, cardiovascular disease, development of certain cancers, and eventually to premature death, it is not surprising that it draws the attention of scientists around the world. The aetiopathology of MetS is complex and still not fully understood. This review focuses on the role of endocrine factors such as cortisol and insulin in the development of MetS. It also takes a look at some of the contributing lifestyle and genetic factors as well as at the current knowledge about its treatment.

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Published

15.12.2013

Issue

Vol. 64 No. 4 (2013)

Section

Review

How to Cite

1.
Endocrine, Lifestyle, and Genetic Factors in the Development of Metabolic Syndrome. Arh Hig Rada Toksikol [Internet]. 2013 Dec. 15 [cited 2025 Jan. 22];64(4). Available from: https://arhiv.imi.hr/index.php/arhiv/article/view/103